The daily ritual
What you'll feel.
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Stronger immune readiness
1,000 mg of beta glucan plus four functional mushrooms, supporting normal, balanced immune function
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Glutathione building blocks
NAC and glycine are two of the three amino acids your body uses to build glutathione
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More balanced days
A calmer, steadier mood through your week
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Clearer thinking
Everyday mental clarity, with no caffeine involved
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Daily vitality
Muscle and bone support that helps you stay active
30-day money back · Free standard shipping · Pause or cancel anytime
See every ingredient and dose →The mechanism
Not absorbed. Recognized.
Beta glucan isn't absorbed — almost none of it reaches your blood. It works by being noticed: as RENEW's four capsules pass through the upper gut, immune cells there sample what goes by, and beta glucan's branching shape is one they're built to recognize.
Published human trials of yeast beta glucan cluster around 250 mg per day — 1,000 mg is disclosed as an amount, not as a claim that more is better.
A shape they recognize
Branched and insoluble — read by Dectin-1 and complement receptor 3. A signaling route, not absorption.
Sampled in the upper gut
Immune cells in and around the gut wall sample what passes through.
The entourage effect
Made to work with your body.
It's an idea sometimes called the entourage effect: rather than chase one thing, RENEW gives everyday support to several of your body's own systems at once. Here's how each part works.*
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A calmer, steadier mood
Saffron is the mood-and-clarity side of the formula. It supports a calmer, steadier mood and everyday mental clarity through your week — the kind you feel in your day, with no caffeine and no crash.
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Everyday immune resilience
Most of your immune system lives in and around your gut, where specialized cells sample whatever passes through. RENEW's four mushrooms — cordyceps, maitake, reishi, and shiitake — bring more beta-glucan fibers through that same pathway, supporting normal, balanced immune function together rather than one at a time.
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Your cells' own defenses
Every minute, turning food into energy leaves a little 'exhaust' behind — free radicals. To keep them in check, each of your cells makes its own antioxidant, glutathione.
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A steady foundation
Vitamin D3 is the everyday nutrient many adults quietly run low on — especially indoors and as the years add up.
The ritual — sixty seconds, once a day.
Four capsules with breakfast, done before the coffee's cool. No powders, no mixing — the routine keeps itself. Saffron's mood support builds over about four weeks; immune support works daily.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The rhythm
Sixty seconds a day. Here’s how it unfolds.
No ladder of promises — just what the ritual looks like, honestly.
Four capsules with breakfast, done before the coffee’s cool.
No powders, no mixing — the routine keeps itself. Clear vegetable capsules, white powder inside, and the entire label is eight ingredients.
Beta glucan works by being noticed, not absorbed.
As the capsules pass through the upper gut, immune cells there sample what goes by — and beta glucan’s branching shape is one they recognize. That’s why it’s a daily ritual, not an occasional one.
Saffron takes its time.
Saffron’s mood support builds over about four weeks; immune support works daily.* Give it the month — and if you don’t feel the difference in 30 days, every penny comes back.
How to use
Take 4 capsules daily, with or without food, day or night.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The label
Six actives. Open any of them.
Per daily serving — four capsules, 30 servings a bottle. Tap an ingredient for what it is and why it’s here.
One day’s 2,533 mg of actives, drawn to scale — tap a band to open it. Vitamin D3’s 25 mcg is real, but a micronutrient: too small to draw.
Beta Glucan 1,3/1,6
1,000 mg
A little-known fiber from baker’s yeast. It isn’t absorbed — as it passes through the upper gut, immune cells there sample what goes by and recognize its branching shape.
GoldenCalm™ Saffron
88.5 mg
A standardized extract of Crocus sativus — the spice this formula is named for, and the most labour-intensive crop in the world. No caffeine anywhere in the bottle.
4-Mushroom Blend
1,020 mg
Cordyceps, maitake, reishi and shiitake — four beta-glucan-rich mushrooms bringing more of the same fiber through the same pathway. Per-mushroom amounts are not broken out.
Beta-glucan rich
NAC + Glycine
225 + 200 mg
Two of the three amino acids your body uses to build glutathione — the antioxidant each of your cells makes for itself.
Glutathione building blocks
Vitamin D3
1,000 IU
25 mcg — the everyday nutrient many adults quietly run low on, especially indoors and as the years add up.
The printed Supplement Facts panel
| Serving Size 4 Capsules · Servings Per Container 30 | |
| Amount Per Serving | % DV |
|---|---|
| Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae) — 1,000 mg | ** |
| Proprietary Mushroom Blend — 1,020 mgCordyceps (Cordyceps sinensis) extract (mycelium), Maitake (Grifola frondosa) powder (mycelial biomass), Reishi (Ganoderma lucidum) powder (mycelial biomass), Shiitake (Lentinula edodes) powder (mycelial biomass) | ** |
| N-Acetyl-L-Cysteine (NAC) — 225 mg | ** |
| Glycine — 200 mg | ** |
| Saffron Extract — 88.5 mg | ** |
| Vitamin D3 — 25 mcg (1,000 IU) | 250% |
** Daily Value not established.
Other ingredients: vegan capsule (cellulose), magnesium stearate. That is the entire list.
BACKED BY PUBLISHED RESEARCH
What the science says about our ingredients.
These published studies examined individual ingredients, not the finished RENEW formula.
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Saffron, studied for mood.
Randomized double-blind placebo-controlled trials of standardized saffron extract, 2017–2025. RENEW uses a different saffron extract and daily amount than these studies.
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Beta-glucans and immune cells.
Randomized controlled trial of Ganoderma β-1,3/1,6-glucan, Foods (MDPI), 2023.
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Glutathione's building blocks.
Foundational glutathione biochemistry. Note: clinical trials of glycine and NAC (e.g. Baylor GlyNAC research) used substantially higher daily amounts than RENEW provides.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Cited studies examined these individual ingredients and do not necessarily reflect this specific formula or its doses.
Why four capsules, and not a gummy.
How much active ingredient a serving carries decides almost everything else about a supplement — the form it takes, how many capsules you swallow, and how long the “other ingredients” line has to be. Here is how that played out for RENEW.
The yeast molecule, not oat or barley fiber
Over 2,500 mg of actives — too much for one capsule
No sugar or syrup needed to carry the dose
Quick answers
See all questions →How do I take RENEW?
Take 4 capsules once a day with a meal and a glass of water — most people pair it with breakfast. One bottle lasts 30 days. For best results, take it consistently; saffron's mood support builds over about four weeks.*
Is it safe with my medications?
Saffron may interact with certain medications, including antidepressants and blood-pressure medicines. If you take prescription medication, are pregnant or nursing, or have a medical condition, check with your doctor first.
Download our one-page "Show your doctor" sheet (PDF) — it lists every ingredient and dose so your physician can review it in one glance.
How does the subscription work? Can I really cancel?
Yes — really. You get 20% off and free shipping, we email you before every charge, and you can pause, skip, or cancel anytime from your account page in one click. Prefer email? Write to support@itsnovera.com and we'll handle it for you.
What if it doesn't work for me?
You're covered by our 30-day money-back guarantee. If you don't feel a difference after a full month, email support@itsnovera.com and we'll refund your entire purchase.
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