With breakfast
Four capsules, a glass of water, done before the coffee's cool.
The ritual
Sixty seconds, once a day.
No thinking required
One bottle, one dose, no powders or mixing — the routine keeps itself.
Consistency compounds
Saffron's mood support builds over four weeks; immunity support works daily.*
THE SCIENCE OF RENEW
Formulated on the evidence.
Purposeful ingredients, selected for the everyday systems that help you feel supported.
Saffron for mood
GoldenCalm™ saffron delivers the plant's active compounds, crocins and safranal, studied for supporting a balanced, positive mood.*
STANDARDIZED CROCINSMushrooms for immunity
Cordyceps, maitake, reishi and shiitake supply beta-glucans that support the everyday activity of your immune cells.*
BETA-GLUCAN RICHNAC + glycine for defense
Glycine and the cysteine that NAC supplies are building blocks your body uses to make glutathione, its own master antioxidant — supporting cellular defense.*
GLUTATHIONE PRECURSORSVitamin D3 foundation
A purposeful 1,000 IU of D3, the nutrient that supports the normal function of the immune system.*
1,000 IU · 250% DV*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Cited studies examined these individual ingredients and do not necessarily reflect this specific formula or its doses.
| Serving Size 4 Capsules · Servings Per Container 30 | |
| Amount Per Serving | % DV |
|---|---|
| Vitamin D3 (as Cholecalciferol) — 25 mcg (1,000 IU) | 250% |
| GoldenCalm™ Saffron Extract — 88.5 mg | ** |
| Proprietary Mushroom Blend — 1,020 mg Cordyceps, Maitake, Reishi, Shiitake (fruiting body extracts) | ** |
| N-Acetyl-L-Cysteine (NAC) — 225 mg | ** |
| Glycine — 200 mg | ** |
** Daily Value not established.
Full transparency
No hidden doses. Every milligram on the label.
| Active ingredient | Per serving (4 caps) |
|---|---|
| Vitamin D3 (as Cholecalciferol) | 25 mcg (1,000 IU) · 250% DV |
| GoldenCalm™ Saffron Extract | 88.5 mg |
| Mushroom Blend + Beta Glucan | 1,020 mg |
| N-Acetyl-L-Cysteine (NAC) | 225 mg |
| Glycine | 200 mg |
Other ingredients: vegan capsule (cellulose), magnesium stearate. Does not contain yeast, wheat, milk, eggs, gluten, soy, gelatin, peanuts, shellfish, artificial colors, or artificial flavors.
BACKED BY PUBLISHED RESEARCH
What the science says about our ingredients.
These published studies examined individual ingredients, not the finished RENEW formula.
Saffron, studied for mood.
Standardized saffron extract has been studied in randomized, placebo-controlled trials for supporting mood and emotional wellbeing in adults.*
Randomized double-blind placebo-controlled trials of standardized saffron extract, 2017–2025. RENEW uses a different saffron extract and daily amount than these studies.
Glutathione's building blocks.
Glycine and the cysteine that NAC supplies are building blocks the body uses to make glutathione, its own master antioxidant — an established biochemical relationship.*
Foundational glutathione biochemistry. Note: clinical trials of glycine and NAC (e.g. Baylor GlyNAC research) used substantially higher daily amounts than RENEW provides.
Beta-glucans and immune cells.
Mushroom-derived beta-glucans have been examined in controlled trials for their activity on immune-cell populations.*
Randomized controlled trial of Ganoderma β-1,3/1,6-glucan, Foods (MDPI), 2023.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Cited studies examined these individual ingredients and do not necessarily reflect this specific formula or its doses.
Your journey
What to expect
Day 1
The foundation begins
NAC, glycine, and vitamin D3 absorb with your first serving — antioxidant and immune support start quietly.*
Week 1–2
The ritual takes hold
Four capsules with breakfast becomes habit, and saffron's mood support builds with each consistent day.*
Week 4
Feel the difference
The point where saffron studies measured mood and clarity benefits. Most people know by now.*
Ongoing
Defenses stay primed
Beta glucan and four mushrooms keep everyday immune readiness going, month after month.*
"I've tried a drawer full of supplements over the years. This is the first one where my daughter noticed the difference before I said a word."
Vegan
Non-GMO
Gluten-Free
3rd-Party Lab Tested
Made in USA
Quick answers
See all questions →How do I take RENEW?
Take 4 capsules once a day with a meal and a glass of water — most people pair it with breakfast. One bottle lasts 30 days. For best results, take it consistently; saffron's mood support builds over about four weeks.*
Is it safe with my medications?
Saffron may interact with certain medications, including antidepressants and blood-pressure medicines. If you take prescription medication, are pregnant or nursing, or have a medical condition, check with your doctor first.
Download our one-page "Show your doctor" sheet (PDF) — it lists every ingredient and dose so your physician can review it in one glance.
How does the subscription work? Can I really cancel?
Yes — really. You get 20% off and free shipping, we email you before every charge, and you can pause, skip, or cancel anytime from your account page in one click. Prefer email? Write to support@itsnovera.com and we'll handle it for you.
What if it doesn't work for me?
You're covered by our 30-day money-back guarantee. If you don't feel a difference after a full month, email or call us and we'll refund your entire purchase.